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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '880129f977f5932926a9f53320ccc0535d47afe53c03bc1ec63975ca5225e452' 
  AND token = '2+zj5FOe/pe5fCcrd1wAmxwIuNH75wJhkvzLxBbRe2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}