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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '364d782d073d3fca7b98dd2d820a61be781cca6f7951c6646fcccb9a3057af7b' 
  AND token = 'cG6CA+IN+6ci+PVnzKTE4mVPFAbMtFvWPMrFiEF4064=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}