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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cad8a38dbbc9d7e0fc47d2901e4e2296481210b9bbd6c91a819153fa84aa1a6' 
  AND token = 'IEjnoAPziOi4Jc6wfRzWpRcErJh5ZwCapaSgtjvOxPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}