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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9388397a5c0625c1b1f3cb30bd832c26a87368aef3ae40afd65bc4826b3d78f2' 
  AND token = '6vL9/OyD70VMGtN+F7y6zrjiZaBhbbnsbwx3Kj/0r5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}