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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b84529fbe0d083878a83e850973caf98180f73ba73b9c4fd84e6e6f6ebf3d579' 
  AND token = '2LlyVcSAHT9RktIsLeaG8md/gw7YGgvxUra8nYYr1Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}