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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44f63deb64825712bf73fe06fd4b017100c3ab2fc704be4082ef13d3418378f6' 
  AND token = 'ONiQv81AAFwu0SbfXebFpA62qo9RHwKPD2X2xl6rWL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}