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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b1dbc7cadb9e815a7f9e6b8a8d8a22aee3535cc53b2e953e88c9929374171c9' 
  AND token = 'X5JWZaZSgfTPEjfDNBEoCqcUnOOiJrEkI9mtXgpGdn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}