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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b814e8b5b9688c1b9130f476ec9f0f2957238a187adf9579b8159aaa512e0367' 
  AND token = 'h5Xc+hnKwwE7OTzQuOSAc9REtG3ovDMCG8vlR3Uup/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}