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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27f452cefa924c1d28d946fc4cd4d9d4ce498160afcc60f7b2edef12615f291' 
  AND token = 'yyUBMsDeek54/SMSJtnbLMX/rivkrRbQ5LFHxtgFAS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}