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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70a72114f66f812c5ced2878275c974c57b743a0a3ff2c46a8cbfeb57debf334' 
  AND token = 'm8jE5YSzpOI4lw+dFa6nbctxwDYYquwa2Zx1oajq7r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}