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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f273b8d586bb05116c49ca6c36fb32e5a25d29942e2ff2c823ba59abacde19b' 
  AND token = 'TlfIFf6K/09ipme2OZW7Fy6R1zbDOPb+mdV0xzZTV+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}