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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351c533167238940f4d47093a0301c78c1bc106a62f7d5339861d71a77d74009' 
  AND token = 'HyfgPkT6fSh4lnfl6W4tWpAaxe39brUp+SPmIKfVXZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}