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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13a57d536ee65afa394b7af55646c263af0c65a7e87a0c5939f2a4216d2077d8' 
  AND token = 'RSnYWl3x0g91NCslCweszYvG4tmFuy874ADfFCJHfTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}