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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1e94dbff48a6b32c803146b771e148068a058edf38d7a737d70a6f55b2b366' 
  AND token = 'H8gp4JeRkyUiyrg73/Dfxi7Ltjwnc8X6q3hP7Vymo5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}