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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c590fb316e06263cd3bca9abd329aae5491aba21cd7d97d4d1ca84c78616fb11' 
  AND token = '80hoQEyv+4ufyRKOWgIAaWFWQsnLN4Rj/s2RhmDxm5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}