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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d8a46dc1dfec0d1023d07d38aaa3e8a75562f60bb1a155904a1fe7e81ac4600' 
  AND token = 'RH7CAVzwKOCQZ9e+FqzocnIOvThARc3+TLokV3xpeb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}