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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac49125f99f381b305fda5dff0e006e1c3b4c2cbea1edbfb24341e1d4abacfe' 
  AND token = 'dPrXSFj/9nTYJvIDwrdJrsxf3xnmZOLra9+jd/QQWZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}