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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caad13ecad7098486fa6a7531019b0ee53bb083a8876095d3991669b1f9cde52' 
  AND token = 'fhg28+a4e1Khk6JmBQbEOErMMT3sAh7sCyvVdhV/dYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}