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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b651a91adfc5537c59439bcd9f7f447a31fc9d331d35e4f975397910374b11' 
  AND token = 'GeFlEAku7lw/TQWSfQ98GF4Q1T0DvTuCjpQsFPPkcew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}