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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5157a415c5c58f2656f7601712ea271b4aba37309f085b090b326b99b8d7ec18' 
  AND token = 'a1XyGW1XOTTbBUcMafv67+Gy/G5WZY1nQrGnqM0P7Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}