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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2537ab17231da05aa17b540e3cb615bc14208538cad042ae970e0a672440b354' 
  AND token = 'Ev9+6OUqwAT1DNQrF/l/OHYPgEyTbDloEDw1E1lZqCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}