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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '254487149f7b4cc55100b8d9b9bece606b3adc286753f079c617f72b2c6dfaeb' 
  AND token = '6VPi6J0k9NrePwtEkQMnjRUapgtG+YUWuYS8pU68Lbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}