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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f48c82f32a96d92a867b29cf7162d4a36a4d1619358e34ff1b8b15b8179ed22' 
  AND token = 'I2fEY+eBFEfeSv+DThT1ZdBi8H+PfUAQBUpicAt3KrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}