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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '407704a0e4b16a1369f125a347da4ebbfd8bde82efa2416396e6073b7398fcf0' 
  AND token = 'Zv2kkuXpL4dSmp0s0hjLCyRVq56aBq0DkhtJn9+j+jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}