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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03c4e5f6af0311980089718dfd7c3932718e61dbac246cb1f21f713f5c5ea370' 
  AND token = '+CXMR2MDspUBcYedN1Vu3CLjHFuy4rhErcdUIS3MiWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}