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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446ca7feb4f2536dd813eb20a24562666abc8b590353ac9b2a07a8e1a4e60208' 
  AND token = 'qqtILhJfS1RTXkxul2SSWhvAoJMfimE9m7nI7/pYnaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}