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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8b32ee97a6fc44dd805c160afa0a79711e166622fe3471a0eb9e47c809a6fa' 
  AND token = '0FlAAyNH4LBxJa4mMbfv0p9vmGb7VvCgjLYTsJdsAiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}