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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e220c371087fc78e5207331a722eb86f25881f60108e0792c3417babe1f72fb6' 
  AND token = 'jD2IHFo7cp7aUk5eKbWdlYQ5j0R5RqWHFG+FllLeaak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}