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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b4757a71926a37f61d7bfe001958e21cd7bf204827f1c25b50b7a3417cdefa' 
  AND token = '2kjf/EcwF8QjWjR4JrtDX+Zi9c6mizvOQmB3rJZMTwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}