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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71fe0c669c60f248aaad6a625688f563928a36a84ba5211f5aad73de53c46bce' 
  AND token = 'k0VvuBm2Hda3tCUxW0eBM5dB+qfVuXwSLLnt/sB99AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}