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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f25a79e584d4fc26c7f4a2ff491832d64109ce08ccc53657e5b7e4fad340fd1' 
  AND token = '3XWaZsylIwiYMO2YRIv47TCNGn9jg8uHYHSa0uTIwLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}