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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef146c23c3b6ecb0718edaa0c0e9b4472dfae053aebbc8e88abf66aa6dae4b1' 
  AND token = 'XVpHHE2OaVv2/r1pZChzQV7bBMwYOniwxUWdNS9q6po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}