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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b1bec3e1562c54c39cc6a8079733b918c99a75ff7cc5a82bc1aa9b0ef9217e1' 
  AND token = 'yNOtoGfaDNJg3Y+R23x3bXs4eG/Pp3zzKXXDn9kF6j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}