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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1994722679ac2fae76446f460de4604da51f3fdbec22d6c100d81158aff60876' 
  AND token = 'yeHe4v01Bx5Y1RQBklLWA3MfPxdepGQ0z3Tu9NCjJjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}