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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '642b7cd7e4c8ce8c66943f9cd6ea81572d96e8a2380ebd13742de33ed596d1dd' 
  AND token = '2ZkURVlGChJMrOpUONu78N2cRKdcK3PhYZ6gUkdA/Rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}