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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a1c570f34c9c68e00e8ed3c10c49dd443b1b8e5e45a0de1a9a5c076644cc704' 
  AND token = 'kmmtPiebQ8phQCfXIBhMTZCunc1c2x8zwBEEHBPHFW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}