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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509b44c750d90e92f4e29d09788b23f7013d74c98d533dbdb2591933cbea439f' 
  AND token = 'waE9lrVmS/8yUMkfryb9CQv50Xs0qJVvfTsP5IA0li8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}