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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c45561e344474d588a58c28643734aeec766aec3a37da101e2cb2eeb67d2785' 
  AND token = '7Hd4GYBp+b3sPw2IPfWKsxFsQPeMX1qMpRi1byXbSSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}