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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204be6c8a421e999669f3d47299a3abed69b11c284f88e1e989f71cac33c4018' 
  AND token = 'hFIjfM+MGnuO3geGrJv5F/6Mhl8v79QXehDhkrVnoMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}