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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5580722321131a9b799a2a4a2b1938791de7e4e1a8005f4ea855f380038df5' 
  AND token = '1kpRr0w/bXxo7bSNZbTJoi5tdJmcRTryH8+UTBnjV7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}