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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8e719893c91258cf12c7d57353defafa2f7ad75d39f232e8e80c3ad400dd65' 
  AND token = 'kEkxWL6tx62tkHMfE0zTl5PPCOTc3Hso7mRXOLzgmpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}