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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5722a4e5f42aa25abbb584a7f462ebe53f3e39693006a4eec840b3b8a2580c5a' 
  AND token = 'p0AnEuzz0kcCiWemYINd/qI//A5PecVvm3k1mQxYFac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}