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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34c2f26e7d1b0a5670b4ec8709015bc68976ce5a161d294d6e503f6534e41a91' 
  AND token = 'x/0gvoCA16lMVdrLQ9U4k0ZDPGdJx5hxr4NPA57gwRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}