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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a590379104bacfb9ababe05a804b648f4e8ac8b52e6aa9cd314d0ffde2e3fbd' 
  AND token = 'o6jE8UIMhvOv2DwdUYLjBUIpx2yfvza7wcL73kb7EJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}