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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452785741bcd5f9f8d117588b18c4c5f2a7497c26410e0607ca0d557eeeef82c' 
  AND token = 'CDXCiUbPUIFn30S89gLbrfxB+rdlp8yVQt75ieLrYto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}