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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0af6d2fba24d7cb09f92e9e64927e97ff06f6918c650f352854093d1d5b8c015' 
  AND token = 'HjnLB4IHxeajzW6R03Mwov7c+oiJqz0qduSwNRSWEQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}