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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2518e43fffe4738679e47be57e5f11c1bafa7282518134a113a01c0112b68ce2' 
  AND token = 'DPOO+fxNPfLfTFTQ3moG7pxB02C0JRoXCSy4Pye4rlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}