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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '657786fa53531cb0ff4f53bd1881cbb3ea2cdf61207d28e8280774488cabd444' 
  AND token = '05E8wAEnf3qEchtLh7DRi453McjLjrX4cEDPfARMJMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}