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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260ab6bfd63506c4ae5c9f22320cf98de708385fdcea53c52c66836266dc0fab' 
  AND token = 'C6eRCt+GfNZg2ed0/SEH5DviIx7Gj1Gq4C5m7InH4Lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}