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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac24e116ace634c5a22f25753a9139348ac3703b83662f23e37e9518014988d' 
  AND token = 'gVOeO2iYsCvPIpSzVY+1ckobiV3XxMUH2tEGoyTAOEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}